1+ months

Bioinformaticists Postdoctoral Scholar

Lawrence Berkeley National Laboratory
Berkeley, California 94720
  • Job Type
  • Job Status
    Full Time

Bioinformaticists Postdoctoral Scholar - 88480

Organization: MB-Molecular Biophys & Integ Bio


Berkeley Lab’s Molecular Biophysics & Integrated Bioimaging Division (https://biosciences.lbl.gov/divisions/mbib/) has an opening for a Bioinformaticists Postdoctoral Scholar. In this role, you will work on the development of computational methods dedicated to the handling of twinned crystallographic data, providing the structural biology community with state of the art algorithmic approaches with tools to handle twinned data in a routine fashion. You will be part of a multidisciplinary team dedicated to solve computational challenges in the experimental sciences, and will collaborate with experimental scientists at the Advanced Light Source and Phenix development team.


What You Will Do:

• Develop likelihood-based twinning-aware target functions for crystallographic refinement and molecular replacement.

• Develop twinning-aware density modification and substructure solution methods.

• Maintain and establish collaborations with relevant internal and external scientists.


Additional Responsibilities as needed:

• Keep an accurate and detailed laboratory (electronic) notebook.

• Maintain a lab-controlled code repository.

• Summarize results in reports and papers submitted for publication and present analysis results at scientific meetings.

• Attend and present data at group meetings.


The posting shall remain open until the position is filled.



• This is a full time, 1 year, postdoctoral appointment with the possibility of renewal based upon satisfactory job performance, continuing availability of funds and ongoing operational needs. You must have less than 4 years paid postdoctoral experience. Salary for Postdoctoral positions depends on years of experience post-degree.

• Full-time, M-F, exempt (monthly paid) from overtime pay.

• This position is represented by a union for collective bargaining purposes.

• Salary will be predetermined based on postdoctoral step rates.

• This position may be subject to a background check. Any convictions will be evaluated to determine if they directly relate to the responsibilities and requirements of the position. Having a conviction history will not automatically disqualify an applicant from being considered for employment.

• Work will be primarily performed at Lawrence Berkeley National Lab, 1 Cyclotron Road, Berkeley, CA.


How To Apply

Apply directly online at and follow the on-line instructions to complete the application process. 


Berkeley Lab (LBNL, http://www.lbl.gov/) addresses the world’s most urgent scientific challenges by advancing sustainable energy, protecting human health, creating new materials, and revealing the origin and fate of the universe. Founded in 1931, Berkeley Lab’s scientific expertise has been recognized with 13 Nobel prizes. The University of California manages Berkeley Lab for the U.S. Department of Energy’s Office of Science.


Equal Employment Opportunity: Berkeley Lab is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status. Berkeley Lab is in compliance with the Pay Transparency Nondiscrimination Provision under 41 CFR 60-1.4 (https://www.dol.gov/ofccp/PayTransparencyNondiscrimination.html).  Click here (https://www.dol.gov/ofccp/regs/compliance/posters/ofccpost.htm) to view the poster: "Equal Employment Opportunity is the Law".


What Is Required:

• Ph.D. in Biophysics, Physics, Mathematics, Chemistry or a related field.

• Experience in crystallographic data analyses.

• Having a sound knowledge or the ability to rapidly develop a deep understanding of the theoretical basis of crystallographic twinning.

• Having a sound knowledge of a variety of numerical methods and the interest and ability to expand this knowledge.

• Programming experience in Python/C++ and the ability (to learn how) to deploy high-performance computational resources.

• Basic skills and understanding of applied mathematics, statistics and machine learning methods.

• Experience using PC, Mac and/or UNIX operating systems.

• Excellent interpersonal skills for working in a diverse team environment and strong written and verbal communication skills to present findings at group meetings and conferences and publish results.

• Strong organizational and record-keeping skills to record experiment results and analyze data.

• Ability to interact with a variety of technical and scientific personnel including Research Associates, Scientists, and Software Engineers.


Additional Desired Qualifications:

• Experience in experimental synchrotron and/or FEL sciences.

• Possess the ability to turn abstract mathematical ideas into actionable algorithms that solve practical problems in the analyses of experimental data.

• Possess the ability to identify fundamental limitations in current data analyses practices and identify approaches that can overcome these problems.


Posted: 2019-12-06 Expires: 2020-02-04

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Bioinformaticists Postdoctoral Scholar

Lawrence Berkeley National Laboratory
Berkeley, California 94720

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